Overview
Extracted from the local paper documentation when available.
Ionizing radiation causes DNA double-strand breaks and disrupts chromatin architecture, potentially leading to chromosomal aberrations and genomic instability. Chromosome conformation capture (3C) technologies, particularly Hi-C, have revolutionized our understanding of three-dimensional genome organization. Here we review the intersection of radiation biology with chromatin conformation studies...
Hi-Cchromosome conformationradiation biologychromatin architectureDNA damagetopologically associating domainsnuclear organization3C technologies
Use Notes
Concise findings and methods pulled from README/SKILL documentation.
Citation
Plain-text citation for quick reuse.
Friedman, Daniel Ari. 2016. Influence of Nuclear Structure on formation of radiation-induced lethal lesions. Int. J. Radiation Biology. DOI: 10.3109/09553002.2016.1144941. URL: https://doi.org/10.3109/09553002.2016.1144941.
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