{
  "title": "A Living Meta-Analysis of the Modafinil Literature",
  "version": "0.1.0",
  "doi": "10.5281/zenodo.20931964",
  "doi_url": "https://doi.org/10.5281/zenodo.20931964",
  "zenodo_record": "https://zenodo.org/records/20931965",
  "record_id": "20931965",
  "publication_date": "2026",
  "resource_type": {
    "title": "Journal article",
    "type": "publication",
    "subtype": "article"
  },
  "creators": [
    {
      "name": "Daniel Ari Friedman",
      "affiliation": null,
      "orcid": "0000-0001-6232-9096"
    }
  ],
  "description": "Manual synthesis cannot keep pace with a fast-growing research literature, and ad-hoc\nreviews bind no evidence to a reproducible pipeline. We present a configurable,\nreproducible meta-analysis framework that takes a single search term and produces a\ncomplete quantitative portrait of its literature. For this instance the term is\nModafinil. The pipeline dispatches across 7 literature\nengines (arXiv, OpenAlex, Semantic Scholar, Crossref, PubMed, SovietRxiv, and ChinaRxiv), each degrading gracefully to a skipped source when an API\nkey or the network is unavailable, then merges and de-duplicates records by a canonical\nidentifier hierarchy (DOI $>$ arXiv ID $>$ Semantic Scholar ID $>$ OpenAlex ID $>$ title\ndigest) into a corpus of $N = 2302$ records spanning 2000--2026\n(26 years). Records are classified into a configurable 6-bucket\nsubfield taxonomy (Clinical Sleep, Cognition, Pharmacology, Psychiatry, Safety, and Neuroscience); the largest subfield is Clinical Sleep\n(64.3\\% of the classified corpus). The corpus grows at a compound annual\nrate of 3.45\\% (mean year-over-year growth 6.3\\%, doubling time\n11.3 years), peaking in 2025 with 112 records.\n\nNon-negative matrix factorization extracts 5 latent topics over a\n500-feature vocabulary, offline deterministic embeddings place every\ntitle, abstract, and (when available) full text in a shared vector space, and\ncitation-network analysis exposes the corpus's internal structure (8,772\nintra-corpus edges across 2204 nodes, 1377 communities,\ngraph density 0.18\\%). Of 38,802 total outgoing\nreferences, 22.6\\% resolve to another record inside the corpus.\nAbstract coverage stands at 55.5\\%, open-access status is known for\n14.4\\% of records, and 40.9\\% have a direct PDF link. An optional,\nLLM-gated knowledge-graph stage scores the 6 hypotheses explored against\nthe evidence. This run produced 18 publication-quality figures.\n\nEvery domain-specific value in this manuscript — the search term, keyword set, engine\nroster, subfield taxonomy, and hypotheses — is injected from a single configuration file\nand the pipeline's own outputs; re-targeting the configuration re-targets the entire\npaper. The result is a reusable architecture for living literature reviews:\ncontinuously re-runnable, evidence-bound syntheses for any topic.\n\nKeywords: modafinil, meta-analysis, literature retrieval, bibliometrics, record de-duplication, full-text mining, document embeddings, citation network, topic modeling, entity extraction, wakefulness, cognitive enhancement, reproducible research\n\n---\nAssociated artifacts\nGitHub release: v0.1.0 (https://github.com/docxology/template_literature_meta_analysis/releases/tag/v0.1.0)\nDOI: https://doi.org/10.5281/zenodo.20931964\nZenodo: https://zenodo.org/records/20931964\nPDF SHA-256: 412d4fcf4b0c2e14fb950f9080f107d81fd9a90dfdf216b9161a13833eff62ff",
  "keywords": [
    "modafinil",
    "meta-analysis",
    "literature retrieval",
    "bibliometrics",
    "record de-duplication",
    "full-text mining",
    "document embeddings",
    "citation network",
    "topic modeling",
    "entity extraction",
    "wakefulness",
    "cognitive enhancement",
    "reproducible research"
  ],
  "files": [
    {
      "name": "Friedman_2026_Living_412d4fcf.pdf",
      "size_bytes": 7314033,
      "checksum": "md5:6504fdc61d497e1665bd6a304c1ffcaf",
      "download_url": "https://zenodo.org/api/records/20931965/files/Friedman_2026_Living_412d4fcf.pdf/content"
    }
  ],
  "related_resources": [
    {
      "type": "repository",
      "url": "https://github.com/docxology/template_literature_meta_analysis"
    }
  ],
  "github_repo": "docxology/template_literature_meta_analysis",
  "github_release_url": "https://github.com/docxology/template_literature_meta_analysis/releases/tag/v0.1.0",
  "release_tag": "v0.1.0",
  "release_name": "A Living Meta-Analysis of the Modafinil Literature (v0.1.0)",
  "pdf_sha256": "412d4fcf4b0c2e14fb950f9080f107d81fd9a90dfdf216b9161a13833eff62ff",
  "pairing_confidence": "strong",
  "pairing_evidence": [
    "github_release_mentions_zenodo_record",
    "zenodo_related_identifier_mentions_release",
    "github_repo_self_linked",
    "title_overlap"
  ],
  "checked_at": "2026-06-26T15:15:42Z"
}